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With a sample size of 24 participants, the 90% confidence interval (CI) for the estimated geometric mean ratio of total exposure would range from 88 to 113% of the geometric mean ratio for icodec and from 89 to 112% of the geometric mean ratio for semaglutide with at least 90% probability

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In murine models, PCS treatment reduced pro-inflammatory factors (IL-1, IL-6, CCL3, and TNF-) and significantly increased the anti-inflammatory factor IL-10, thereby further alleviating hepatic inflammation

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Horvth, Adrienn Menyhrt, Manfredi Rizzo, Solomon Tesfaye, Vincenza Spallone Frontiers in Clinical Diabetes and Healthcare.2026;[Epub] CrossRef Early autonomic neuropathy in prediabetes: an overlooked driver of cardiometabolic risk Marcio J