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Penn Researchers Use AI to Surface Unreported GLP-1 Side Effects in Reddit Posts AI, Research and Innovation / April 10, 2026 By using AI to analyze more than 400,000 Reddit posts, Penn researchers have identified patient-reported symptoms associated with GLP-1s, the popular weight-loss and diabetes drugs semaglutide and tirzepatide, that may not be fully captured in clinical trials or regulatory documents

Those numbers matter

Loose stools or more frequent trips to the bathroom can happen in the early weeks

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Patients should never obtain Ozempic without a valid prescription following comprehensive medical assessment including review of medical history, current medications, renal function, and appropriateness of treatment

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