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They boost blood flow, calm inflammation, and turn on repair signals

It was reported that aldose reductase inhibitors, such as epalrestat, reduced ROS levels and retinal lipid peroxidation in diabetic rats, suggesting a therapeutic avenue (54)

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The pathological features of IS include oxidative stress and inflammation, exacerbated by ROS, chemokines, and cytokines (Chen et al., 2020b

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