The system Xc/GSH/GPX4 pathway was the first discovered and today is recognized as the centerpiece of the ferroptosis mechanism (Figure 5) [22,66]
This property has been attributed to its gastric juice protein origin
And why is it often called the best antioxidant
J Invest Med
Therefore, targeted activation of antioxidant systems, especially the GSH system, is an essential treatment strategy to protect cardiomyocytes against oxidative damage

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