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The same researchers conducted a larger intervention in 42 children with autistic disorder who had evidence of reduced methylation capacity or GSH:GSSG in which they were supplemented with folinic acid and methyl-cobalamin for 3 months [48]
Jahan E, Almansour R, Ijaz K, Baptista S, Giordan LB, Ronto R, et al
Ternary Complex Factor-Serum Response Factor Complex-Regulated Gene Activity Is Required for Cellular Proliferation and Inhibition of Apoptotic Cell Death
Reported benefits include fat metabolism support, improved athletic performance and recovery, more energy, and possible heart and cognitive benefits