A trustworthy provider will clearly explain how your data is stored and shared
Physical Protection: Store vials upright to prevent leaks and avoid stacking them
Previously, we have already developed and validated a similar PET marker for the GLP1R receptor, [ 68 Ga]Ga-DO3A-Exendin-4, in non-human primates 9,10
The growing clinical trial data in Phase III showing efficacy of dual GLP-1/amylin co-activation over current GLP-1 monotherapy are a game-changer for the market, delivering the clinical evidence required to support FDA regulatory approval, positive payer coverage decisions, and physician adoption in the increasingly competitive diabetes and obesity treatment landscape
In order to monitor the intracellular translocation of agonists, as well as GLP-1Rs, we used fluorescently labeled exendin-4, exendin-phe1, and exendin-asp3 conjugates, with fluorescein isothiocyanate (FITC) at position K12, which we previously found useful for labeling GLP-1R 28
Sheehan D, Meade G, Foley V, Dowd C (2001) Structure, function and evolution of glutathione transferases: implications for classification of non-mammalian members of an ancient enzyme superfamily