Feeling tired, out of balance, or just not quite yourself
It has been reported that there is no reduction in its secretion in patients with T2DM [13] but a nearly total loss of insulinotropic effect is observed, even at supraphysiological concentrations, implying the existence of GIP resistance [14]
If fatigue, mood changes, or reduced motivation are significant during treatment, its worth discussing testosterone levels with your provider
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Patients taking certain medicationsparticularly other GLP-1 drugs, sulfonylureas, or insulinmay experience compounded effects requiring dosage modification by their provider