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Protective effect of trimetazidine on myocardial mitochondrial function in an ex-vivo model of global myocardial ischemia

Although research remains at the preclinical animal stage, the product has become an important tool for dissecting glucose metabolism disorders and diabetes and developing novel hypoglycemic agents, with its key advantage lying in nicotinamide pathway regulation and NAD+ stabilization

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This increase in norepinephrine stimulates -adrenergic receptors in the brains satiety center, inducing a stress-response signal that diminishes hunger