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The prescribing information confirms no modification is needed for mild, moderate, or severe renal impairment (eGFR 15 mL/min) or for mild to moderate hepatic impairment 1

In some cases, if the sensitivity is bothersome, a provider might suggest a slight dose reduction to see if the symptoms resolve

Environmental stressorsincluding ultraviolet radiation, air pollution, and ozone, as well as physiological factors such as hormonal fluctuations, aging, exposure to pesticides, microbial antigens, and high-sugar diets can elevate ROS levels on the ocular surface, triggering oxidative stress (Honisch et al., 2023)

Lower somatostatin expression is an early event in diabetic retinopathy and is associated with retinal neurodegeneration

Saugy et al ., 2006

Some states also license nutritionists through alternative pathways, typically requiring a masters degree in nutrition or a related field plus supervised experience