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Among 110 enrolled patients, the ferroptosis-based combination achieved an objective response rate (ORR) of 31.8% in ICI-naive populations and 22.5% in ICI-refractory subgroups, with adverse events predominantly limited to grade 12 gastrointestinal discomfort and fatigue

One such observation has been made in the study, which indicated the cross-reactivity of antibodies for previous coronaviruses endemic among the human population 131 , and recent studies have shown the presence of IgG seropositivity for OC43 and NL63 in individuals who have not been exposed to SARS-CoV-2 forming immune responses against SARS-CoV-2 132

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