The body converts it to methylcobalamin and adenosylcobalamin so that it can be used
IM stands for Intramuscular, meaning the shot goes directly into the muscle
While some minor side effects like a bit of temporary soreness around the injection site can happen, its not very common
Conditions associated with elevated B12 levels include: Liver disease : Hepatocellular damage releases stored B12 into circulation, with levels correlating with disease severity in conditions such as cirrhosis, hepatitis, and hepatocellular carcinoma Renal impairment : Reduced kidney function decreases B12 clearance, leading to accumulation Haematological malignancies : Myeloproliferative disorders, acute leukaemia, and polycythaemia vera can elevate B12 through increased production of B12-binding proteins (transcobalamins) Solid tumours : Certain cancers, particularly those affecting the liver or gastrointestinal tract, may elevate B12 levels A specific concern relates to cyanocobalamin in patients with Leber's hereditary optic neuropathy , a rare mitochondrial disorder
That is why treatment for a confirmed deficiency often starts with a higher frequency, sometimes weekly, for a defined period
(6) Deficiency can be missed in settings such as malabsorption, autoimmune gastritis, certain medication use, and nitrous oxide exposure