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Bron: Efficacy and Safety of Semaglutide for Weight Loss in Obesity Without Diabetes: A Systematic Review and Meta-Analysis, Journal of the ASEAN Federation of Endocrine Societies (2022)

The cardiovascular effects of tirzepatide have been evaluated in clinical trials, with heart rate monitoring included as part of comprehensive cardiovascular assessments

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If youre taking thyroid medication, hormone therapy, antidepressants, or anything that affects blood sugar, its worth checking with your doctor first

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If you carry the C-allele of this variant, your receptor may be more responsive, meaning lower doses could produce stronger appetite suppression