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References Abdulghani AA, Sherr A, Shirin S et al (1998) Effects of topical creams containing vitamin C, a copper-binding peptide cream and melatonin compared with tretinoin on the ultrastructure of normal skin - A pilot clinical, histologic, and ultrastructural study

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Many also lack proper placebo controls, which could mean some benefits come from people feeling hopeful about their treatment rather than the glutathione itself