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The presence of autonomic dysfunction, some sensory loss like anosmia, ageusia, sleep disorders, unilateral onset and persistent asymmetry of symptoms, positive response to dopaminergic therapy, and levodopa-induced dyskinesia can strengthen the diagnosis (Jankovic, 2008

Wang, J.Y

In Vitro 20 , 265271 (2006)

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IGF-1 Receptor Signalling: The PI3K-Akt-mTOR and MAPK Pathways Binding of IGF-1 LR3 to IGF-1R activates two interlocking cascades