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Respiratory quotient: Measured through indirect calorimetry, this variable provides insights into metabolic efficiency, showing the balance between carbohydrate and fat oxidation during exercise

In another phase 3 clinical trial , people with obesity and type 2 diabetes taking tirzepatide lost around 13%--15% of their body weight over 72 weeks

It is likely that zonulin release is initiated by dysbiosis and gliadin by a similar mechanism

Melzer-Cohen C, Chodick G, Husemoen LLN, Rhee N, Shalev V, Karasik A

If you have type 2 diabetes and take other glucose-lowering medications, discuss hypoglycemia risk and whether medication adjustments are needed

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