[DOI] [PubMed] [Google Scholar] Dunn AJ (2006) Effects of cytokines and infections on brain neurochemistry
Cysteine preservation confers resistance to glutathione-depleted cells against ferroptosis via CDGSH iron Sulphur domain-containing proteins (CISDs)
Parkinson's disease is characterized by the accumulation of misfolded proteins, such as alpha-synuclein, which can activate microglia and cause them to release pro-inflammatory molecules that can harm neurons
Senkyunolide I alleviates renal Ischemia-Reperfusion injury by inhibiting oxidative stress, endoplasmic reticulum stress and apoptosis
Under normal conditions, Nrf2 is anchored in the cytosol through its interaction with Kelch-like ECH-associated protein 1 (Keap1), which serves as a substrate adapter protein for an E3 ubiquitin ligase complex (Zhang et al
In the process of physiological ageing, both systemic and tissue-specific systems show functional downfalls, which, when projected to the brain, translate into weakening defence and metabolic strain resulting from age-dependent declines of the cardio-vascular system and overall decreases in metabolism