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Factors favouring transdermal absorption are high lipid solubility and a good regional blood supply to the site of application (therefore, the thorax and abdomen are preferred to limbs)

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doi: 10.1007/s001250100616 24 DilixiatiDWailiATuerxunmaimaitiATaoLZebibulaARexiatiM

4 Still, this research shows what happens when you stop the medications suddenly without a gradual decrease in dose (a taper), and with adequate lifestyle support alongside it

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The delayed gastric emptying effect of exenatide may affect the absorption of oral medications