The research, funded by a biotech called BlueWater Biosciences, would still need to be confirmed in humans
The role of PPARalpha in lipid metabolism and obesity: focusing on the effects of estrogen on PPARalpha actions
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Diabetes Obes Metab 22(12):24872492 Verma S, Bhatta M, Davies M, Deanfield JE, Garvey WT, Jensen C, et al (2023) Effects of once-weekly semaglutide 2.4 mg on C-reactive protein in adults with overweight or obesity (STEP 1, 2, and 3): Exploratory analyses of three randomised, double-blind, placebo-controlled, phase 3 trials
2,3 In a Phase I multiple-dose clinical trial conducted in healthy adults, pharmacokinetics were dose-proportional, accompanied by reductions in both fasting and oral glucose tolerance glucose levels
