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In a mouse multiple sclerosis (MS) model, a GABA-A receptor agonist, homotaurine, shows promise.[ref] Animal models of Sjgrens syndrome show promise for using GABA to ameliorate symptoms

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Among these, the valine-to-isoleucine substitution (V717I) was one of the first identified mutations, playing a pivotal role in the development of the amyloid cascade hypothesis of AD pathogenesis

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