Studies show GLP-1-only agonists (like semaglutide) produce 15-17% weight loss at maximum doses, making it the foundation of the triple-agonist effect
Theyre going to need psychological counselling, behaviour change, nutritional support from that moment on to help them sustain healthier behaviour in the long term, to keep the weight off, she said
The strategy reflects a broader shift in MASH drug development from treating fibrosis alone toward addressing the underlying metabolic dysfunction that drives inflammation and liver injury
Health Serv Outcomes Res Method
Other links Review article advising resistance training in people taking GLP-1 agonists Paper that examines weight loss after 1 year of exercise or GLP-1 drugs More in-depth look at appetite and exercise behaviours in that study Study finding risk for RED-s in 30% of triathletes, including the tools that can be used to identify risk factors Cycling teams paying young riders big salaries More episodes View all episodes The Art and Science of Perfect Pacing (Members' Exclusive Show, Now Unlocked for All) 42:32|Quick heads up before we start: this is not a brand new episode
doi: 10.1007/S11154-023-09807-3 13 MarsoSPDanielsGHBrown-FrandsenKKristensenPMannJFENauckMAet al