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Since peptides are not foreign to our bodies, they are generally well-tolerated

This dual mechanism promotes weight loss by increasing energy expenditure through glucagon receptor activation while enhancing insulin secretion and suppressing appetite via GLP-1 receptor activation

The requirement for cationic CPP in our study is consistent with findings from other studies, where CPPs with hydrophobic motifs did not significantly enhance cell uptake 60

2024 Apr 3;17(4):461

For example, nanoparticles have been constructed with individual or multiple versions of the full spike protein or RBD region and presented in high-order antigen arrays in native-like conformations (reviewed in ref