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Iliceto S, Scrutinio D, et al

writing original draft preparation: AP, ES, DS, and AB

Benefits for Gut Health: Targets pathogens without harming beneficial bacteria Helps eliminate mold, yeast, and biofilm Improves immune surveillance in the gut lining Supports wound healing and epithelial integrity Clinical Context: LL-37 is ideal for patients with dysbiosis, recurrent infections, SIFO (small intestinal fungal overgrowth), or mold-related illness

70,71 Additionally, the exploration of GLP-1R positive allosteric modulators (PAMs) offers a new regulatory approach that could enhance the therapeutic profile of small-molecule GLP-1R agonists

Its loss is not simply an aesthetic concern