However, in mice that received peripheral administration of a high dose of fluorescein-ghrelin, the fluorescein signal was observed not only in the ARC and ME but also in the AP and paraventricular nucleus (PVN), suggesting that circulating ghrelin can traverse fenestrated capillaries and reach certain CVOs (55)
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[68] Chen JK, Chen TT, Nguyen M, Huang L, Chang J, Friesen R, et al
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