The assumption of proportional hazards was evaluated with the generalized Schoenfeld approach on the TriNetX platform, with aHRs recalculated for specific time frames if initial assumptions were not met
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personal or family history of medullary thyroid carcinoma or MEN2 (a class-level GLP-1 caution that may extend to combination products)
Glutathione: Glutathione is an antioxidant tripeptide that plays a key role in supporting the bodys natural detoxification processes and defending cells against oxidative stress.*
Notably, total IGF-I and IGFBPs were unchanged over this short-duration window, dissociating the observed bone-growth effect from sustained IGF-1 axis activation in this model