It can compromise the integrity of painstakingly synthesized peptides, introduce variables you can't account for, and ultimately render your data useless
Because B12 status governs homocysteine, it features in cognition research: in the randomized, placebo-controlled VITACOG trial, homocysteine-lowering B vitamins (including B12) slowed the rate of brain atrophy in older adults with mild cognitive impairment an effect concentrated in those with elevated baseline homocysteine[3]
1 Vitamin B 12 has been demonstrated to be safe in doses up to 1,000 times the recommended dietary allowance and is safe in pregnancy
Payers audit D51.0 because it supports more expensive ongoing B12 injection billing
But with the extra receptors in the neuron connections (synaptic cleft), over-firing occurs
One criticism is that syringes are too big at 3ml and ga, should be insulin 100iu needles