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Given the similarities between the brain's and retina's vascular systems, these findings suggest that GLP-1R agonism could also protect the brain's microvasculature, preserving the integrity of the blood-brain barrier and improving cerebral blood flow

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CLINICAL RELEVANCE Evidence that glutathione is involved in the metabolic disturbances which underlie diabetes, obesity, insulin resistance, and the metabolic syndrome continues to grow as well

The pharmacological active ingredient is identical

This work is supported by the National Key Research & Development Program (2022YFC2603900), Beijing Natural Science Foundation (JQ24055), and the National Natural Science Foundation of China (22175189, 52373127)