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Retatrutide shows comparable HbA1c improvements in Phase 2 trials, but it lacks the comprehensive diabetes-specific trial data that tirzepatide possesses through the SURPASS program

Supplements such as vitamin D, magnesium, vitamin B12, coenzyme Q10, probiotics, omega-3 fatty acids, melatonin, S-adenosylmethionine, and acetyl-l-carnitine are discussed for their potential benefits in FM management through various mechanisms, including anti-inflammatory effects, modulation of neurotransmitters, and improvement of mitochondrial function

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Other warnings Intensive therapy for megaloblastic anemia may result in hypokalemia, thrombocytosis, and life-threatening complications