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doi: 10.3389/fendo.2021.694284 26
For example, a dysbiotic microbiota can promote ferroptosis by suppressing SLC7A11 expression, which limits cysteine uptake and GSH synthesis, while concurrently enhancing acyl-CoA synthetase long-chain family member 4 (ACSL4)-driven lipid peroxidation (41)
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Altering its levels without a clear medical indication could potentially disrupt these vital processes
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