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But if you have a family history of kidney disease and youre thinking about long-term B12 supplementation, it might be worth asking your doctor about MTHFR testing

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A US grain is 64.78971 milligrams - this is usually rounded in manufacture down to a multiple of 5 mg (so that a #3 contains 30 mg, and a #4 contains 60 mg, while a #1 may be 8 mg or 10 mg depending on manufacturer

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This suggests that robust NAD+ repletion helps preserve antioxidant capacity