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The likely groups to avoid it, still being studied, include people with a personal or family history of medullary thyroid cancer, multiple endocrine neoplasia type 2, severe stomach-emptying problems, type 1 diabetes, or pregnancy
After restarting birth control for a third time, Dunham came off it again around the time she started semaglutide because her estrogen levels were too high
Its a test of how organizations manage rising costs, employee expectations, legal complexity, and operational scale all at once
10.1038/nature17998 Nature 136 ZhangK.HashimotoK
Common side effects occurring in more than 5% of patients include: Nausea (affecting up to 30% of patients, particularly during dose escalation) Diarrhea (1316% incidence) Vomiting (810%) Constipation (68%) Abdominal pain and dyspepsia Injection site reactions (erythema, pruritus) These gastrointestinal symptoms are typically mild to moderate, transient, and diminish over time as tolerance develops
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