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4.2.2 Glutathione peroxidase 4 (GPX4) GPX4 is a crucial enzyme inhibiting ferroptosis, protecting cell membranes from oxidative damage by reducing lipid peroxides
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Abstract Since Albert Szent-Gyrgyi discovered it and it became used in treating scurvy, vitamin C has attracted interest in many studies due to its unique properties
doi: 10.3390/antiox11051034 Summary Keywords osteoarthritis, ferroptosis, metabolic reprogramming, immunometabolic crosstalk, iron homeostasis, lipid peroxidation, inflammatory microenvironment Citation Xia S, Li L, Shi Z, Sun N and He Y (2025) Ferroptosis in osteoarthritis: metabolic reprogramming, immunometabolic crosstalk, and targeted intervention strategies
Yet, analysis of data from NHANES 2003-2018, a US national cross-sectional survey of 39,438 adults, found an inverse association between selenium intake and stroke, with daily intakes of 105 g/day linked to the lowest stroke risk (93)
Common Questions What are the common signs of low glutathione levels
