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(2011) Unidirectional cross-activation of GRPR by MOR1D uncouples itch and analgesia induced by opioids

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Misuse at doses above 200mg can trigger hallucinations, confusion, and respiratory depressionabuse potential is particularly high among teenagers seeking psychoactive effects

Rush AJ, Trivedi MH, Wisniewski SR, Nierenberg AA, Stewart JW, Warden D, et al

References Scientific Review Scientific Contributor and Reviewer Reviewed for scientific accuracy, 14 June 2026 Lyophilised powder: store at -20 C or below, away from light and moisture