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2 Material and methods 2.1 Data extraction and quality assessment This study was conducted in accordance with the PRISMA guidelines (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) to report systematic reviews (Supplementary Material)
If you are experiencing intolerable side effects, contact your provider about potentially staying at your current dose longer before escalating, or adjusting your protocol in other ways
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Formulation and route of delivery are not interchangeable and carry real clinical consequences
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