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The MTHFR gene variation : Not everyone with Hashimotos will have this gene variation, but I do find it to be a common culprit relating to nutrient deficiencies and poor detoxification

Each spectrum was segmented using the simple rectangular bucket option of the AMIX software (Bruker Biospin) in fixed rectangular regions (buckets) of 0.02 ppm width which were successively integrated

Supplementing with B12 shots ensures they receive adequate amounts without compromising their dietary choices

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Suggested macro split (lean bulk or recomp): Protein: 1.01.2g per lb of body weight Carbs: 1.52.5g per lb (higher on training days) Fats: 0.30.4g per lb (favor omega-3 and monounsaturated sources) Adequate carbohydrate intake is essential to fuel IGF-1-mediated muscle growth and recovery by supporting insulin sensitivity and glycogen replenishment. Tipton & Wolfe, Journal of Sports Sciences Nutrient Timing Pre-Workout: Complex carbs + fast-digesting protein Post-Workout (with IGF-1 LR3): High-glycemic carbs + Collagen Protein or whey to maximize amino acid delivery Before Bed: GH-supportive stack (e.g., ZMT + Krill Oil) to support overnight repair Training Protocol Recommendations Because IGF-1 LR3 enhances recovery and cellular growth , it works best in high-volume hypertrophy or recomposition training blocks

Epub 2020 Jan 15