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ANDA filing counts, available from FDA databases, provide the most direct leading indicator

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Positive role of CCAAT/enhancer-binding protein homologous protein, a transcription factor involved in the endoplasmic reticulum stress response in the development of colitis

We implemented the Bayesian Confidence Propagation Neural Network (BCPNN) for sensitivity analysis, with its specific computational formula detailed in Supplementary Table 1

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