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For transduction, the cells were plated in 6-well plates at a concentration of 2.5 10 5 cellswell 1

Mechanistically, UA enhances mitochondrial -oxidation and potentially activating skeletal muscle adenosine 5-monophosphate-activated protein kinase (AMPK) signaling and upregulating mitochondrial respiratory chain complex activity to exert ergogenic effects

6 , 244ra89 (2014)