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Research indicates that the biologically active region of GHRH is largely contained within this N-terminal fragment, making Sermorelin a useful proxy for studying hypothalamic signaling dynamics

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Uma vez que a grelina, alm da libertao de GH, tambm promove a motilidade gastrointestinal, o efeito procintico de um mimtico seletivo da grelina biologicamente plausvel e coincide com os dados em roedores de Venkova et al., 2009

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