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(Midi does not prescribe this or other unapproved peptides.) What the science says: Theres promising preclinical (aka animal or lab) data on MOTS-c, and early research suggests that MOTS-c may improve metabolism by activating the AMPK pathway and help reverse age-related insulin resistance

The resulting compound has reported serum half-life and blood-brain-barrier permeability sufficient for oral and intragastric administration in rodent studies, which is unusual for a peptide derivative of this size

There is no natural substitute that replicates GLP-1 medications

These are different categories of care

, Ziegler M., and Baur J