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High levels of acetaldehyde can cause amnesia, which is why someone can wake up the day after a night of heavy drinking and wonder, "What happened last night." When ethanol intake is high, alcohol dehydrogenase activity is insufficient to process the amount of acetaldehyde that accumulates, which can lead to acetaldehyde buildup in the liver

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One night you fall asleep fine, and the next youre staring at the ceiling, tired but wired, while the clock keeps moving