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DHA deficiency is associated with dysfunctions in the dopaminergic system [150], but supplementation with -3 PUFAs has been shown to improve attention and reduce impulsivity

Moreover, parent and physician reports from various surveys suggest that several children exhibit moderate to notable improvements in eye contact, communication, social interactions, and sleep patterns after supplement intervention

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Other mitochondrial citrate cycle enzymes, such as alpha-ketoglutarate dehydrogenase and isocitrate dehydrogenase can also be activated by Ca 2+ [21, 22]