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Beyond efficacy: Ensuring safety in peptide therapeutics

Preclinical studies suggest that MSC-Exos can alleviate ferroptosis-induced damage by enhancing antioxidant defenses, mitigating oxidative stress, upregulating anti-ferroptotic regulators, and suppressing lipid peroxidation

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Moreover, some NAD + precursors have shown side effects, such as the use of NA at certain doses that might be limited due to skin flushing or induction of insulin resistance 332,333

Magnesium Magnesium is involved in more than 300 enzymatic reactions in the human body, touching everything from energy production and protein synthesis to muscle contraction and nerve signalling

Predicting anticancer peptides with Chous pseudo amino acid composition and investigating their mutagenicity via Ames test