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Ongoing studies in the STEP program will provide further insights into the effects of once-weekly semaglutide 2.4 mg in a broader population [22]

GLP-1 analogues offer more than just weight loss

Greater receptor binding: Semaglutide binds more effectively to GLP-1 receptors, producing stronger signaling

2 GLP-1 Lys 26 may form a polar interaction with the receptor, which is presumably enhanced by Arg 20 in exenatide, but creates no steric hindrance

Can You Use Your FSA or HSA According to IRS rules, FSA and HSA funds cant be used for dietary supplements, including GLP-1 patches, unless a doctor prescribes them for a diagnosed medical condition

Published online 2025