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Older individuals: Aging leads to decreased gastric acid production, reducing B-12 release from bound proteins

Numerous foods contain B vitamins, and most people can get enough through a balanced diet that includes eggs, fish, meat, nuts, and dark leafy greens

The longer effective tissue exposure is consistent with the actin-sequestration mechanism, which depends on intracellular accumulation rather than transient extracellular signaling

Even though this marker is considered to be the most sensitive marker for B12 deficiency, at the time of this writing, it is not readily available

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