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To gain insight into the epigenetic mechanisms underlying lipedema pathogenesis, a genome-wide DNA methylation analysis was performed on subcutaneous adipose tissue samples collected from from non-affected adipose tissue from no-lipedema group two cohorts of patients

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Importantly, tirzepatide carries an FDA boxed warning for risk of thyroid C-cell tumors, and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN2)

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