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First, there's the obvious: needle aversion

Since obesity is associated with an increased risk of cardiovascular disease, the ongoing SELECT study is investigating whether once-weekly semaglutide 2.4 mg will reduce the risk of having cardiovascular events in patients with overweight or obesity and with prior cardiovascular disease [61]

Our products are produced using a freeze-drying process (lyophilization), which helps maintain their integrity and stability during transit, typically for up to 34 months

how you handle it between storage and injection also matters

The BBB is a dynamic, highly selective semipermeable membrane that serves as a protective filter, preventing harmful toxins and pathogens from entering the brain while allowing essential nutrients and oxygen to pass through

PMID 29364588