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Approved GLP-1 Agonists for Weight Loss Currently, there are two GLP-1R agonists approved for the treatment of obesity, Saxenda (liraglutide) and Wegovy (semaglutide) , both developed by Novo Nordisk and approved by the FDA in 2014 and 2021, respectively

It also helps reduce hunger signals in the brain, enabling individuals to naturally consume fewer calories without persistent cravings

Fiber Constipation is one of the most common side effects of GLP-1 medications, and fiber-rich foods are one of the best ways to manage it

Metformin, a first-line oral medication, reduces glucose production in the liver and improves insulin sensitivity

Glucagon opposes insulin action, which creates a more complex interaction profile with diabetic medications