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There is a very complex coordination involving the varius branches of the Autonomic Nervous System with these cells in the gastric mucosa, which contributes to many of the abnormalities seen in patients with Gastroparesis

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Together, they can boost GH levels up to five to ten times above baseline

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Since levothyroxine requires an acidic gastric environment for optimal dissolution and absorption, and its absorption can be affected by the rate of gastric emptying, patients may experience variations in thyroid hormone levels when starting semaglutide therapy