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Low ROS levels activate cell survival signaling pathways, such as the unfolded protein response and Nrf2 pathways, whereas high ROS levels activate cell death signaling pathways, such as apoptosis and necroptosis pathways 43

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When a peptide is loaded in a pen cartridge, the same storage rules apply

A sinusoidal voltage at the 5 kHz frequency was applied to the needle electrode, whereas the low voltage probe (Tektronix TPP1000) was adopted for collecting the current flowing through the sampling resistance (R = 1 k)