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NEJM, 2022

Thioctic (lipoic) acid: A therapeutic metal-chelating antioxidant

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Ive seen some patients on the maximal dose have zero side effects and Ive seen other patients on a very minimal dose and have more severe side effects

170 In the presence of conditionally pathogenic bacteria, SIRT1 activation alleviates intestinal oxidative stress via the FOXO1SOD2 axis

We, therefore, aimed to systematically review the molecular and pathophysiological mechanisms of hyperprolactinemia and obesity, focusing on key central and peripheral pathways, supported by current experimental and clinical evidence ( Figure 1 )