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Begin at the lowest dose and increase gradually as tolerated

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Because CJC-1295 raises IGF-1 downstream, people with a history of cancer need closer oversight

Its benefits are maximized when used as an adjunct to a reduced-calorie diet and increased physical activity

This limitation may particularly have influenced the ITT analyses, whereas non-compliance was of less concern in the per-protocol analyses in which patients were censored at treatment cessation or switch